--- title: Nutrasource Blog | Toxicology description: Toxicology | Follow the Nutrasource blog for commercialization tips, regulatory updates, and more - written by our senior scientists and regulatory specialists for the health products industry. --- [![SGS-Nutrasource-Logo-RGB-18mm_PRIMARY-1](https://blog.nutrasource.ca/hs-fs/hubfs/SGS-Nutrasource-Logo-RGB-18mm_PRIMARY-1.png?width=350&height=55&name=SGS-Nutrasource-Logo-RGB-18mm_PRIMARY-1.png)](https://www.nutrasource.ca/)   # Nutrasource Blog ## [New Approach Methods in Toxicology: Innovations in In Vitro Testing for Chemical Safety](https://blog.nutrasource.ca/blog/new-approach-methods-toxicology) Posted by Benjamin Arceneaux, Junior Toxicologist on Tue, May 14, 2024 - [Tweet](https://twitter.com/share) [![](https://blog.nutrasource.ca/hubfs/iStock-1494029118.jpg)](https://blog.nutrasource.ca/blog/new-approach-methods-toxicology) The current paradigm used to determine the safety of an ingredient involves several *in vitro*, animal, and human studies. However, recent advances in *in vitro* methodologies have spurred the development of new approach methods, or NAMs. A NAM is defined by the US Environmental Protection Agency (EPA) as, “a technology, methodology, approach, or combination that can provide information on chemical hazard and risk assessment to avoid the use of animal testing”. NAMs are also commonly defined to include *in silico*, *in chemico*, and *in vitro* assays, as well as information about the exposure of chemicals in the context of hazard assessment. *In silico* methods are computational in nature, *in chemico* refers to purely chemical methods, such as testing a chemical by seeing if it reacts with another chemical or isolated protein in the absence of cells or tissues, and *in vitro* refers to experiments conducted in cell or tissue cultures. The ultimate goal of NAMs is to replace, reduce, or refine the use of animal testing in chemical safety assessment. [Read More](https://blog.nutrasource.ca/blog/new-approach-methods-toxicology) 0 Comments [Click here to read/write comments](https://blog.nutrasource.ca/blog/new-approach-methods-toxicology#comments-listing) Tags: [Toxicology](https://blog.nutrasource.ca/blog/topic/toxicology) [All posts](https://blog.nutrasource.ca/blog/all) - [Return to Home](http://www.nutrasource.ca/) - [Solutions](http://www.nutrasource.ca/solutions) - [Markets](http://nutrasource.ca/markets/) - [Resources](http://nutrasource.ca/resources/) - [About Us](http://nutrasource.ca/about/) [![SUBSCRIBE BY EMAIL](https://no-cache.hubspot.com/cta/default/295381/a6581d92-fb4f-47f5-bec4-7a9e5f5e64e3.png)](https://cta-redirect.hubspot.com/cta/redirect/295381/a6581d92-fb4f-47f5-bec4-7a9e5f5e64e3) ### Recent Posts ### Categories - [Dietary Supplements/Natural Health Products (53)](https://blog.nutrasource.ca/blog/topic/dietary-supplements-natural-health-products) - [Regulatory (48)](https://blog.nutrasource.ca/blog/topic/regulatory) - [Claims (23)](https://blog.nutrasource.ca/blog/topic/claims) - [Concept to Claim (23)](https://blog.nutrasource.ca/blog/topic/concept-to-claim) - [Clinical Trials (21)](https://blog.nutrasource.ca/blog/topic/clinical-trials) - [Product Marketing (16)](https://blog.nutrasource.ca/blog/topic/product-marketing) - [Product Testing & Certifications (16)](https://blog.nutrasource.ca/blog/topic/product-testing-certifications) - [Probiotics (11)](https://blog.nutrasource.ca/blog/topic/probiotics) - [market access (10)](https://blog.nutrasource.ca/blog/topic/market-access) - [Foods & Beverages (9)](https://blog.nutrasource.ca/blog/topic/foods-beverages) - [Cannabis (5)](https://blog.nutrasource.ca/blog/topic/cannabis) - [Events (5)](https://blog.nutrasource.ca/blog/topic/events) - [Pharmaceuticals (5)](https://blog.nutrasource.ca/blog/topic/pharmaceuticals) - [Team Talk (5)](https://blog.nutrasource.ca/blog/topic/team-talk) - [Non-GMO (3)](https://blog.nutrasource.ca/blog/topic/non-gmo) - [Omega-3s (3)](https://blog.nutrasource.ca/blog/topic/omega-3s) - [Animal Supplements (2)](https://blog.nutrasource.ca/blog/topic/animal-supplements) - [ingredients (2)](https://blog.nutrasource.ca/blog/topic/ingredients) - [Animal Health (1)](https://blog.nutrasource.ca/blog/topic/animal-health) - [Sport Nutrition (1)](https://blog.nutrasource.ca/blog/topic/sport-nutrition) - [Toxicology (1)](https://blog.nutrasource.ca/blog/topic/toxicology) see all